Sodium hydride → HCID 66995623、化合物
反応式
[H-].[Na+].[F:3][C:4]1[CH:5]=[CH:6][C:7]([O:11][CH3:12])=[C:8]([OH:10])[CH:9]=1.[Cl:13][C:14]1[CH:19]=[C:18]([N+:20]([O-:22])=[O:21])[CH:17]=[CH:16][C:15]=1F>CN(C=O)C.O>[Cl:13][C:14]1[CH:19]=[C:18]([N+:20]([O-:22])=[O:21])[CH:17]=[CH:16][C:15]=1[O:10][C:8]1[CH:9]=[C:4]([F:3])[CH:5]=[CH:6][C:7]=1[O:11][CH3:12]参加物
6
実験手順
Sodium hydride (60% disp. oil, 0.281 g) was added to a solution of 5-fluoro-2-methoxyphenol (1.0 g) in DMF (20 ml) and stirred at RT for 30 min. 2-Chloro-1-fluoro-4-nitrobenzene (1.23 g) was added and the mixture stirred at RT for 16 h then diluted with water and extracted with diethylether. The organics were dried and evaporated under reduced pressure, yield 1.95 g.
後処理
- stirringthe mixture stirred at RT for 16 h
- extractionextracted with diethylether
- customThe organics were dried
- customevaporated under reduced pressure, yield 1.95 g
出典と根拠
- ORDレコード
- ord-9fb3416c5f2248b99e880a0a237c3a52
- 出典データセット
- uspto-grants-2013_03
- 特許番号
- US08394986B2
反応ノート
読み込み中…