Glutaric anhydride → 4-[(3-Ethynylphenyl)carbamoyl]butanoic acid
反応式
[C:1]1(=[O:8])[O:7][C:5](=[O:6])[CH2:4][CH2:3][CH2:2]1.[C:9]([C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][CH:17]=1)[NH2:14])#[CH:10]>ClCCl>[C:9]([C:11]1[CH:12]=[C:13]([NH:14][C:5]([CH2:4][CH2:3][CH2:2][C:1]([OH:7])=[O:8])=[O:6])[CH:15]=[CH:16][CH:17]=1)#[CH:10]参加物
4
実験手順
Glutaric anhydride (215 mg, 1.9 mmol) was dissolved in anhydrous dichloromethane (7 ml) and followed by the addition of 3-ethynylaniline (200 mg, 1.7 mmol). The mixture was allowed to stir at room temperature for 6 hours before the solvent was evaporated under reduced pressure to provide the product as a white solid (363 mg, 99%);
後処理
- customwas evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-b51d7cb6b41e41718e3f39d76b7da4bc
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745229B2
反応ノート
読み込み中…