Sodium Dithionite → 2-Hydroxyiminostilbene
反応式
[CH:1]1[C:2](=[O:16])[CH:3]=[CH:4][C:5]2=[N:6][C:7]3[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=3[CH:9]=[CH:10][C:11]=12.[O-]S(S([O-])=O)=O.[Na+].[Na+]>C(Cl)(Cl)Cl.O>[CH:1]1[C:11]2[CH:10]=[CH:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[NH:6][C:5]=2[CH:4]=[CH:3][C:2]=1[OH:16]参加物
5
実験手順
Title compound 374 (170 mg, 0.82 mmol) was solubilized in CHCl3 (5 mL) and a saturated solution of Na2S2O4 in water was added (20 mL). The mixture was stirred for 3 hours. The 2 layers were split and the organic layer was dried over sodium sulfate, filtered and evaporated to afford title compound 375 (110 mg, 65%). MS (m/z): 209.9 (M+H).
後処理
- customThe 2 layers were split
- dry with materialthe organic layer was dried over sodium sulfate
- filtrationfiltered
- customevaporated
出典と根拠
- ORDレコード
- ord-ba540f4ce36545f9804af770d91f2ba6
- 出典データセット
- uspto-grants-2013_03
- 特許番号
- US08399452B2
反応ノート
読み込み中…