反応式
[NH2:1][C:2]1[CH:11]=[C:10](O)[C:9]2[C:4](=[CH:5][CH:6]=[C:7](Cl)[CH:8]=2)[N:3]=1.[F:14][C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][C:16]=1B(O)O.[CH3:25][O:26][C:27]1[CH:34]=[CH:33][CH:32]=[CH:31][C:28]=1[CH:29]=O.[N:35]1[CH:40]=[CH:39][CH:38]=[C:37]([CH2:41][NH2:42])[CH:36]=1>>[F:14][C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][C:16]=1[C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([NH:42][CH2:41][C:37]3[CH:36]=[N:35][CH:40]=[CH:39][CH:38]=3)[CH:8]=2)[N:3]=[C:2]([NH:1][CH2:29][C:28]2[CH:31]=[CH:32][CH:33]=[CH:34][C:27]=2[O:26][CH3:25])[CH:11]=1参加物
5
実験手順
The title compound, MS: m/e=483.5 (M+H+), was prepared in accordance with the general method of example 30 from 2-amino-6-chloro-4-hydroxyquinoline (CAS 64319-84-2), 2,5-difluorophenylboronic acid, 2-methoxybenzaldehyde and 3-picolylamine.
出典と根拠
- ORDレコード
- ord-29ab4f83fbdb4220a42d6dcbf3b66981
- 出典データセット
- uspto-grants-2013_03
- 特許番号
- US08399674B2
関連ノート
読み込み中…