Benzyl Alcohol → Benzyl 4-carboxyphenylacetate

HRID 1950653ノート

反応式

HRID 1950653 の反応式
C(C1C=CC(CC(O)=O)=CC=1)=[O:2].C(O)C1C=CC=CC=1.[CH:21]([C:23]1[CH:28]=[CH:27][C:26]([CH2:29][C:30]([O:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)=[O:31])=[CH:25][CH:24]=1)=[O:22]>>[CH2:33]([O:32][C:30]([CH2:29][C:26]1[CH:25]=[CH:24][C:23]([C:21]([OH:2])=[O:22])=[CH:28][CH:27]=1)=[O:31])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

参加物

4

反応物 3

HCID 244Benzyl AlcoholHCID 113441872-(4-formylphenyl)acetic AcidHCID 19966221Benzyl 2-(4-formylphenyl)acetate

生成物 1

HCID 19966080Benzyl 4-carboxyphenylacetate収率 80.6%

実験手順

Synthesized from (4-formylphenyl)acetic acid (1 g) and benzyl alcohol (730 mg) according to an analogous synthetic method to Example 806, benzyl (4-formylphenyl)acetate (1.4 g) was used according to an analogous synthetic method to Preparation Example 53 to provide the title compound (1.2 g).

後処理

  1. customwas used according to an analogous synthetic method to Preparation Example 53

出典と根拠

ORDレコード
ord-c45b78abdee74abfaacf72d90fd3e6ec
出典データセット
uspto-grants-2013_03
特許番号
US08399520B2

反応ノート

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