HCID 54512044、化合物 → 1-Propanol, 3,3,3-trifluoro-, 1-acetate
反応式
[C:1]([O:4][CH:5]=[CH:6][C:7]([F:10])([F:9])[F:8])(=[O:3])[CH3:2]>[Pd]>[C:7]([CH2:6][CH2:5][O:4][C:1]([CH3:2])=[O:3])([F:10])([F:9])[F:8]参加物
3
実験手順
3,3,3-Trifluoropropenyl acetate (7.1. g) was hydrogenated in a glass pressure bottle overnight at 65°-70° C. using 0.1 g 10% Pd/C as catalyst and a maximum H2 pressure of 35 psi. The catalyst was separated by centrifugation, providing 6.7 g of 97% pure CF3CH2CH2OAc (93% yield). Bp 112°-113° C. [lit. 112° C.; B. T. Golding, P. J. Sellars, and W. P. Watson, J. Fluorine Chem., 30 (1985) 153]. 1H NMR: δ4.29 (t, 2 H, J=6.4 Hz), 2.4 (m, 2 H), 2.07 (s, 3H). 19F NMR: δ-65.8 (t, J=10.4 Hz).
後処理
- customwas hydrogenated in a glass pressure bottle overnight at 65°-70° C.
- customThe catalyst was separated by centrifugation
出典と根拠
- ORDレコード
- ord-44d7a08e22f94c73be955801c289b26a
- 出典データセット
- uspto-grants-1998_07
- 特許番号
- US05777184
反応ノート
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