Benzoyl Peroxide → 3-(Bromomethyl)biphenyl

HRID 1957003

反応式

HRID 1957003 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[Br:14]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[C:8]1([C:4]2[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=2)[CH2:1][Br:14])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 125643-MethylbiphenylHCID 67184N-bromobutanimide

生成物 1

HCID 38644053-(Bromomethyl)biphenyl

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 3-methylbiphenyl (5.23 g, 31.1 mmol), N-bromosuccinimide (5.56 g, 31.2 mmol), benzoyl peroxide (135 mg, 0.56 mmol), and carbon tetrachloride (150 ml) is refluxed for 17 h. The mixture is concentrated in vacuo and the residue is purified by flash column chromatography (hexane) to give 3-phenylbenzyl bromide.

後処理

  1. temperatureis refluxed for 17 h
  2. concentrationThe mixture is concentrated in vacuo
  3. customthe residue is purified by flash column chromatography (hexane)

出典と根拠

ORDレコード
ord-e6b235cc9e144fd1a618c058180307e5
出典データセット
uspto-grants-1998_07
特許番号
US05780498

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