Methylamine → N-Methyl-2-phenylacetamide

HRID 1957275ノート

反応式

HRID 1957275 の反応式
[C:1]1([CH2:7][C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:11][NH2:12]>C1C=CC=CC=1>[CH3:11][NH:12][C:8](=[O:9])[CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 6329MethylamineHCID 7679Phenylacetyl chloride

生成物 1

HCID 81274N-Methyl-2-phenylacetamide

試薬・触媒・溶媒 1

HCID 241Benzene溶媒2 回

実験手順

Dissolved 15 g(0.1 mol) of phenylacetyl chloride in 100 ml of benzene. While stirring on a magnetic stirrer, introduced methylamine into the benzene solution at 20°-30° C. Followed the procedure of compound 3-1 for the purification of the product to yield N-methyl phenylacetamide as light yellowish crystal. Yield, 12 g (80%).

後処理

  1. customFollowed the procedure of compound 3-1 for the purification of the product

出典と根拠

ORDレコード
ord-78eab7f62f12455e952eaf02f1cbcc37
出典データセット
uspto-grants-1998_07
特許番号
US05783605

反応ノート

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