Nitric Acid → 1-Methanesulfonyl-3-nitro-5-trifluoromethylbenzene
反応式
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([C:11]([F:14])([F:13])[F:12])[CH:6]=1)(=[O:4])=[O:3].[N+:15]([O-])([OH:17])=[O:16]>S(=O)(=O)(O)O>[CH3:1][S:2]([C:5]1[CH:6]=[C:7]([C:11]([F:12])([F:13])[F:14])[CH:8]=[C:9]([N+:15]([O-:17])=[O:16])[CH:10]=1)(=[O:4])=[O:3]参加物
4
反応条件
- 温度
- 80 °C
実験手順
1-methanesulfonyl-3-trifluoromethylbenzene (220 mg; 1 mmol) was dissolved at 0° C. in 3 mL 98% sulfuric acid and 2 mL of 100% HNO3 were added. The mixture was heated 2 hours at 80° C. and then poured onto ice; a precipitate was isolated: 110 mg (0.40 mmol; 40% yield) of 1-methanesulfonyl-3-nitro-5-trifluoromethylbenzene were obtained as a solid.
後処理
- additionpoured onto ice
- customa precipitate was isolated
出典と根拠
- ORDレコード
- ord-09a81b0d57e74495b174a0766abaa28e
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08410100B2
反応ノート
読み込み中…