Acetic Acid → HCID 67239262、化合物

HRID 1963680ノート

反応式

HRID 1963680 の反応式
C(O[C:9]1[CH:14]=[C:13]([S:15]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=2)(=[O:17])=[O:16])[C:12]([F:26])=[CH:11][C:10]=1[C:27]1[CH:32]=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=1)C1C=CC=CC=1.[H][H].C(O)(=[O:38])C>[Pd]>[F:26][C:12]1[CH:11]=[C:10]([C:27]2[C:32]([OH:38])=[CH:31][CH:30]=[C:29]([F:33])[CH:28]=2)[CH:9]=[CH:14][C:13]=1[S:15]([C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)(=[O:16])=[O:17]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 68089499HCID 68089499、化合物HCID 178418361HCID 178418361、化合物

生成物 1

HCID 67239262HCID 67239262、化合物

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

A suspension of the product of step (ii) (838 mg) in acetic acid (30 ml) and 10% Pd/C (200 mg) was stirred under 2 bar pressure of hydrogen for 30 min. The catalyst was removed by filtration and the filtrate was evaporated to give the subtitle compound, yield 630 mg.

後処理

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated

出典と根拠

ORDレコード
ord-9d80e81b84a043689c79567b3e3b7abd
出典データセット
uspto-grants-2013_04
特許番号
US08415394B2

反応ノート

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