4-(3-nitrophenyl)-1H-pyrazole → 3-(1H-pyrazol-4-yl)aniline
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:11]=[N:12][NH:13][CH:14]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>[Pd].C(OCC)(=O)C>[NH:12]1[CH:11]=[C:10]([C:6]2[CH:5]=[C:4]([CH:9]=[CH:8][CH:7]=2)[NH2:1])[CH:14]=[N:13]1参加物
4
実験手順
A 5 mL ethyl acetate solution of 300 mg (1.59 mmol) of 4-(3-nitrophenyl)-1H-pyrazole was added to 30 mg of 5% Pd—C, and stirred under a hydrogen atmosphere at room temperature overnight. The reaction solution was filtered through celite, and the filtrate was condensed and dried to give 252 mg of 3-(1H-pyrazol-4-yl)aniline (yield: 99%).
後処理
- filtrationThe reaction solution was filtered through celite
- customcondensed
- customdried
出典と根拠
- ORDレコード
- ord-16db744df37c4bc68bed8563600a5825
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08415479B2
反応ノート
読み込み中…