Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate → Trimethyl 1,2,4-benzenetricarboxylate

HRID 1964747ノート

反応式

HRID 1964747 の反応式
[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH:6]=[CH:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12]>C1(C)C=CC=C(C)C=1.[Pt]>[C:15]([O:17][CH3:18])(=[O:16])[C:1]1[C:2](=[CH:3][C:4](=[CH:5][CH:6]=1)[C:7]([O:9][CH3:10])=[O:8])[C:11]([O:13][CH3:14])=[O:12]

参加物

4

反応物 1

HCID 60136166Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate

生成物 1

HCID 17159Trimethyl 1,2,4-benzenetricarboxylate収率 65%

試薬・触媒・溶媒 2

HCID 23939Platinum触媒HCID 7929M-Xylene溶媒

実験手順

Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (200 mg, 0.78 mmol) is mixed with 305 mg of 5 percent by weight platinum on a carbon support in m-xylene (30 ml). The reaction mixture is refluxed with the reflux apparatus being open to air for 4 days. The residual platinum on carbon is then filtered off and the filtrate is concentrated down to a clear colorless gel. The desired product is obtained with a 65 percent yield. The yield is determined by GC/MS using a dodecane as an internal standard.

後処理

  1. temperatureThe reaction mixture is refluxed with the reflux apparatus
  2. filtrationThe residual platinum on carbon is then filtered off
  3. concentrationthe filtrate is concentrated down to a clear colorless gel

出典と根拠

ORDレコード
ord-7d4aa9dc9d6b4c53994987875b36a38c
出典データセット
uspto-grants-2013_04
特許番号
US08415496B2

反応ノート

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