Trimethyl cyclohex-5-ene-1,2,4-tricarboxylate → Trimethyl cyclohexane-1,2,4-tricarboxylate

HRID 1964748ノート

反応式

HRID 1964748 の反応式
[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH:6]=[CH:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12].[H][H]>C(Cl)Cl.[Pd]>[CH:1]1([C:15]([O:17][CH3:18])=[O:16])[CH2:6][CH2:5][CH:4]([C:7]([O:9][CH3:10])=[O:8])[CH2:3][CH:2]1[C:11]([O:13][CH3:14])=[O:12]

参加物

5

反応物 2

HCID 60136166Trimethyl cyclohex-5-ene-1,2,4-tricarboxylateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 12616206Trimethyl cyclohexane-1,2,4-tricarboxylate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 6344Dichloromethane溶媒

実験手順

A solution of trimethyl cyclohex-5-ene-1,2,4-tricarboxylate (0.50 g, 1.9 mmol) in methylene chloride (15 ml) containing a catalytic amount of palladium on carbon (150 mg, 5 percent Pd/C, 7.5 mg Pd, 4 mole percent) is stirred at room temperature under balloon pressure of hydrogen gas for 2 hours, at which point GC-MS analysis shows complete conversion. Filtration and removal of the solvent provides trimethyl cyclohexane-1,2,4-tricarboxylate as a clear, colorless gel (0.42 g, 1.6 mmol, 85 percent yield).

後処理

  1. filtrationFiltration and removal of the solvent

出典と根拠

ORDレコード
ord-c562221a12504ad9bc19e4a84a0d2b49
出典データセット
uspto-grants-2013_04
特許番号
US08415496B2

反応ノート

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