Iodine → HCID 178516519、化合物
反応式
[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][N:3]=1.C([O-])([O-])=O.[K+].[K+].[I:15]I.OS([O-])(=O)=O.[K+]>O>[OH:1][C:2]1[C:7]([I:15])=[C:6]([OH:8])[CH:5]=[CH:4][N:3]=1参加物
6
反応条件
- 温度
- 100 °C
実験手順
A mixture of 2,4-dihydroxypyridine (1.0 eq), K2CO3 (1.0 eq), and water was stirred at 100° C. so that it became homogeneous. With continued stirring and heating, I2 (1.0 eq) was added in portions, causing the evolution of gas. When the solid I2 was consumed, the mixture was cooled and acidified with aqueous KHSO4 (1.0 eq), generating a precipitate. The precipitate was collected by filtration, rinsed with water, and stored under high vacuum, to give 2,4-dihydroxy-3-iodopyridine.
後処理
- stirringWith continued stirring
- temperatureheating
- customWhen the solid I2 was consumed
- temperaturethe mixture was cooled
- filtrationThe precipitate was collected by filtration
- washrinsed with water
出典と根拠
- ORDレコード
- ord-c55d733421a444529c3510bfaeac415c
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745454B2
反応ノート
読み込み中…