2-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane → 5,8-Dioxaspiro[3.4]octane-2-methanol

HRID 1966814ノート

反応式

HRID 1966814 の反応式
C([O:8][CH2:9][CH:10]1[CH2:13][C:12]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:11]1)C1C=CC=CC=1>CO.[Pd]>[CH2:11]1[C:12]2([O:17][CH2:16][CH2:15][O:14]2)[CH2:13][CH:10]1[CH2:9][OH:8]

参加物

4

反応物 1

HCID 120735822-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane

生成物 1

HCID 120735835,8-Dioxaspiro[3.4]octane-2-methanol

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

Palladium/carbon (10%) was added to a solution of 2-[(benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane (22.0 gm, 94.0 mmol) (step c) in methanol and the mixture was stirred at room temperature under hydrogen balloon for about 4 hours. It was filtered through celite bed and residue was washed with methanol. The combined filtrate was concentrated under reduced pressure.

後処理

  1. filtrationIt was filtered through celite bed and residue
  2. washwas washed with methanol
  3. concentrationThe combined filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-7de2674c31184f9e89e447183164d3c9
出典データセット
uspto-grants-2013_04
特許番号
US08420666B2

反応ノート

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