Hydrochloric Acid → 2-Nitro-5-phenoxybenzaldehyde

HRID 1968773

反応式

HRID 1968773 の反応式
C[O:2][CH:3](OC)[C:4]1[CH:9]=[C:8]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=[CH:6][C:5]=1[N+:17]([O-:19])=[O:18].Cl.O>C1COCC1>[N+:17]([C:5]1[CH:6]=[CH:7][C:8]([O:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[CH:9][C:4]=1[CH:3]=[O:2])([O-:19])=[O:18]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 962Water2 回HCID 34804522-(Dimethoxymethyl)-1-nitro-4-phenoxybenzene

生成物 1

HCID 442030822-Nitro-5-phenoxybenzaldehyde

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

To a solution of 2-(dimethoxymethyl)-1-nitro-4-phenoxy-benzene (7.4 g, 0.0256 mol) in THF (80 mL) was added 12 N HCl (10 mL) and water (20 mL). The resulting mixture was stirred at room temperature for 2 days. Water was then added, and the mixture was extracted with diisopropyl ether. The organic layer was separated, washed with 10% aqueous NaHCO3 solution and then with water, dried (MgSO4), filtered, and concentrated to yield a yellow solid.

後処理

  1. extractionthe mixture was extracted with diisopropyl ether
  2. customThe organic layer was separated
  3. washwashed with 10% aqueous NaHCO3 solution
  4. dry with materialwith water, dried (MgSO4)
  5. filtrationfiltered
  6. concentrationconcentrated
  7. customto yield a yellow solid

出典と根拠

ORDレコード
ord-6f0a927456d549b8915e35b82fbfb6da
出典データセット
uspto-grants-2013_04
特許番号
US08426429B2

関連ノート

読み込み中…