Hydrochloric Acid → ethyl (2S)-2-amino-3-(3-methoxyphenyl)propanoate
反応式
C1(C(C2C=CC=CC=2)=[N:8][C@H:9]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=2)C=CC=CC=1.Cl>C1COCC1>[CH3:18][O:17][C:13]1[CH:12]=[C:11]([CH:16]=[CH:15][CH:14]=1)[CH2:10][C@@H:9]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[NH2:8]参加物
4
実験手順
To a 100-mL round-bottomed flask was added ethyl N-(diphenylmethylidene)-3-methoxyphenylalaninate (912 mg, 2.35 mmol), 5 M hydrochloric acid (0.471 mL, 2.35 mmol) and THF (20 mL). The reaction mixture was stirred at room temperature for 1 h. The solvent was removed in vacuo to give the crude product, ethyl 3-methoxyphenylalaninate which was used without further purification.
後処理
- customThe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-db602ce7c5634d0ea62a0daa9f50ff4d
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08431563B2
反応ノート
読み込み中…