Hydrochloric Acid → HCID 66582562、化合物
反応式
C1(C(C2C=CC=CC=2)=[N:8][C@H:9]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[N:12]=2)C=CC=CC=1.Cl>C1COCC1>[CH3:18][O:17][C:13]1[N:12]=[C:11]([CH2:10][C@@H:9]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[NH2:8])[CH:16]=[CH:15][CH:14]=1参加物
4
実験手順
To a 100-mL round-bottomed flask was added ethyl N-(diphenylmethylidene)-3-(6-methoxy-2-pyridinyl)alaninate (1.81 g, 4.66 mmol) and 5N hydrochloric acid (1.86 mL, 9.32 mmol), and THF (20 mL). The reaction mixture was stirred at room temperature for 30 min. The solvent was removed in vacuo to give crude ethyl 3-(6-methoxy-2-pyridinyl)alaninate as a light-yellow tar, which was used without purification.
後処理
- customThe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-91200790e8c147e983b4ec1e0be78d1a
- 出典データセット
- uspto-grants-2013_04
- 特許番号
- US08431563B2
反応ノート
読み込み中…