Benzene → Phthalimide

HRID 1973123ノート

反応式

HRID 1973123 の反応式
[C:1]1(=O)[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.C=C(CCCC#N)CCCC#[N:18].C1C=CC=CC=1>P(=O)(O)(O)O.O>[C:1]1(=[O:6])[NH:18][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12

参加物

6

反応物 3

HCID 241BenzeneHCID 6811Phthalic AnhydrideHCID 30165315-Methylenenonanedinitrile

生成物 1

HCID 6809Phthalimide収率 199.4%

試薬・触媒・溶媒 2

HCID 1004Phosphoric Acid触媒HCID 962Water溶媒

反応条件

温度
240 °C

実験手順

225 g (1.52 moles) of phthalic anhydride, 121.5 g (0.75 mole) of 5-methylene-1,9-nonanedinitrile, 300 cc of benzene, 40 g of water and 2 g of phosphoric acid were placed in a 1-liter autoclave. The autoclave was closed, then purged with dry nitrogen. Following purging, the reactor was heated to 240° C for a period of 4 hours. After cooling, the reaction mixture was filtered. The filter solid, after being washed in 300 cc of benzene, filtered and dried, yielded 220 g of phthalimide having a melting point of 234°-238° C. Yield 100 percent.

後処理

  1. customThe autoclave was closed
  2. custompurged with dry nitrogen
  3. customFollowing purging
  4. temperatureAfter cooling
  5. filtrationthe reaction mixture was filtered
  6. washThe filter solid, after being washed in 300 cc of benzene
  7. filtrationfiltered
  8. customdried

出典と根拠

ORDレコード
ord-235c45dc691d4055bfddb37114316e02
出典データセット
uspto-grants-1976_12
特許番号
US03996239

反応ノート

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