Water → 3-Chloro-N,N-dimethyl-4-(2-nitrobut-1-en-1-yl)aniline
反応式
[Cl:1][C:2]1[CH:9]=[C:8]([N:10]([CH3:12])[CH3:11])[CH:7]=[CH:6][C:3]=1[CH:4]=O.[N+:13]([CH2:16][CH2:17][CH3:18])([O-:15])=[O:14].C([O-])(=O)C.[NH4+].O>C(O)CC>[CH3:11][N:10]([CH3:12])[C:8]1[CH:7]=[CH:6][C:3]([CH:4]=[C:16]([N+:13]([O-:15])=[O:14])[CH2:17][CH3:18])=[C:2]([Cl:1])[CH:9]=1参加物
6
実験手順
A solution of 36.8 g of 2-chloro-4-dimethylaminobenzaldehyde, 25 ml of 1-nitropropane and 20 g of ammonium acetate in 150 ml of 1-propanol is refluxed for 15 hours. The mixture is then poured into 1.5 l of water whereupon the compound separates as a viscous red oil. Recrystallization twice from aqueous acetic acid yields 5.0 g of the compound, melting at 90°-91°.
後処理
- customRecrystallization twice from aqueous acetic acid
出典と根拠
- ORDレコード
- ord-5cd59fdbbb5d499e831ee925c4e442b0
- 出典データセット
- uspto-grants-1976_12
- 特許番号
- US03996381
反応ノート
読み込み中…