Acetic Acid → Carbendazim

HRID 1973427

反応式

HRID 1973427 の反応式
[C:1]([NH:3][C:4](=[O:7])[O:5][CH3:6])#[N:2].[C:8]1(N)[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH2:14].C(O)(=O)C>O>[N:2]1[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH:14][C:1]=1[NH:3][C:4]([O:5][CH3:6])=[O:7]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 7243O-PhenylenediamineHCID 89023Methyl N-cyanocarbamate

生成物 1

HCID 25429Carbendazim収率 72%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
50 °C

実験手順

A solution of 5.0 parts of the salt of methyl cyanocarbamate with o-phenylenediamine and 1.5 parts of acetic acid in 25 parts of water is refluxed for 30 minutes. The solution is cooled to 50° C. and filtered. The product is washed with water and dried in vacuo at 95° C. This procedure gives 3.3 parts (72% yield) of 2-benzimidazolecarbamic acid, methyl ester.

後処理

  1. filtrationfiltered
  2. washThe product is washed with water
  3. customdried in vacuo at 95° C

出典と根拠

ORDレコード
ord-3da346668bc146ccb8ddc4a1ee5b499a
出典データセット
uspto-grants-1976_12
特許番号
US03997553

関連ノート

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