HCID 53847304、化合物 → HCID 22795184、化合物
反応式
C[O:2][C:3]1[CH:4]=[C:5]([C@H:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]2[N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[CH:6]=[CH:7][CH:8]=1>Br.O>[OH:2][C:3]1[CH:4]=[C:5]([C@H:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]2[N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[CH:6]=[CH:7][CH:8]=1参加物
4
実験手順
(1) The above oil (19g) was boiled in 47% hydrobromic acid (60 ml) for six hours. The cooled solution was diluted with water, washed with ether, basified and ether extracted. The dried extract was evaporated. The residue was triturated with petroleum ether (b.p. 40° to 60° C) and crystallised from petroleum ether (b.p. 60° to 80° C)/ ethyl acetate to give cis-2-(3-hydroxyphenyl)-1-pyrrolidinocyclohexane (12g), m.p. 124° to 126° C.
後処理
- washwashed with ether
- extractionether extracted
- extractionThe dried extract
- customwas evaporated
- customThe residue was triturated with petroleum ether (b.p. 40° to 60° C)
- customcrystallised from petroleum ether (b.p. 60° to 80° C)/ ethyl acetate
出典と根拠
- ORDレコード
- ord-239a5fa649b640afa3a2d6d118becc84
- 出典データセット
- uspto-grants-1976_12
- 特許番号
- US03998843
反応ノート
読み込み中…