Epichlorohydrin → HCID 21490522、化合物

反応式

[CH:1]([C:4]1[CH:10]=[CH:9][CH:8]=[C:6]([OH:7])[C:5]=1[OH:11])([CH3:3])[CH3:2].[CH2:12]([CH:14]1[O:16][CH2:15]1)[Cl:13].[OH-:17].[Na+]>O>[CH:1]([C:4]1[C:5]([O:11][CH2:15][CH:14]([OH:16])[CH2:12][Cl:13])=[C:6]([O:7][CH2:15][CH:14]([OH:17])[CH2:12][Cl:13])[CH:8]=[CH:9][CH:10]=1)([CH3:3])[CH3:2]

参加物

反応条件

温度: 40 °C

実験手順

22.9 g. of 3-isopropylcatechol, 56 g. of epichlorhydrin and 0.2 g. of sodium hydroxide, dissolved in a few drops of water, are stirred together for 21 days at 40° C under a nitrogen atmosphere. The excess of epichlorohydrin is distilled off under reduced pressure. The resulting oil is dissolved in chloroform, washed twice with water and purified by molecular distillation at 10-3 mm.Hg 32.55 g. of impure 1,1'-[(3-isopropyl-o-phenylene)dioxy]-bis-(3-chloropropan-2-ol) are obtained.