N-bromobutanimide → HCID 19101519、化合物

HRID 1974439ノート

反応式

HRID 1974439 の反応式
[C:1](=[C:4]([C:9]([O:11][CH3:12])=[O:10])[C:5]([O:7][CH3:8])=[O:6])([CH3:3])[CH3:2].C1C(=O)N([Br:20])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[C:1](=[C:4]([C:9]([O:11][CH3:12])=[O:10])[C:5]([O:7][CH2:8][Br:20])=[O:6])([CH3:3])[CH3:2]

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 51620841,3-Dimethyl 2-(propan-2-ylidene)propanedioate

生成物 1

HCID 19101519HCID 19101519、化合物収率 109.7%

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 26. 4 grams (0.15 mol) of dimethyl isopropylidenemalonate and 27.5 grams (0.15 mol) of n-bromosuccinimide were stirred in 150 mL carbon tetrachloride containing 1.0 grams benzoyl peroxide. The mixture was refluxed for 16 hours under nitrogen. The reaction was cooled in ice and the succinimide was filtered off and washed with carbon tetrachloride. The solvent was removed under reduced pressure to yield 41.3 grams of impure bromomethyl methyl isopropylidenemalonate as an oil which was used without further purification.

後処理

  1. temperatureThe mixture was refluxed for 16 hours under nitrogen
  2. temperatureThe reaction was cooled in ice
  3. filtrationthe succinimide was filtered off
  4. washwashed with carbon tetrachloride
  5. customThe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-d858b7c4856443bf821a86446567fecc
出典データセット
uspto-grants-1994_02
特許番号
US05283165

反応ノート

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