Water → HCID 18990361、化合物

HRID 1974736ノート

反応式

HRID 1974736 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH2:5]O.[NH:14]1[CH:18]=[CH:17][CH:16]=[CH:15]1.O>O1CCOCC1>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH2:5][C:15]1[NH:14][CH:18]=[CH:17][CH:16]=1

参加物

5

反応物 3

HCID 962WaterHCID 8027PyrroleHCID 189903745-(Hydroxymethyl)-3-nitrobenzene-1,2-diol

生成物 1

HCID 18990361HCID 18990361、化合物

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

反応条件

温度
100 °C

実験手順

A solution containing 1.0 g of 3,4-dihydroxy-5-nitrobenzylalcohol and 5.0 ml of pyrrole in 3.0 ml of dioxane was heated for 5 h at 100° C. Water was added and the solution was extracted with dichloromethane. The solvent was evaporated and the residue was purified in a silicagel column using toluene-acetic acid-dioxane (18:1:1) mixture as an eluent. Yield 0.42 g (33%), m.p. 115°-118° C.

後処理

  1. extractionthe solution was extracted with dichloromethane
  2. customThe solvent was evaporated
  3. customthe residue was purified in a silicagel column

出典と根拠

ORDレコード
ord-da548f3fbfa24705b69d57bf669feb24
出典データセット
uspto-grants-1994_02
特許番号
US05283352

反応ノート

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