Ethanol → HCID 135736970、化合物

HRID 1974803ノート

反応式

HRID 1974803 の反応式
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[S:12][C:13]3[CH:19]=[C:18]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH:17]=[CH:16][C:14]=3[N:15]=2)=[CH:7][CH:6]=1)(=O)C.[OH-].[Na+].C(O)C>O>[OH:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]2[S:12][C:13]3[CH:19]=[C:18]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH:17]=[CH:16][C:14]=3[N:15]=2)=[CH:9][CH:10]=1

参加物

5

反応物 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 19100366HCID 19100366、化合物

生成物 1

HCID 135736970HCID 135736970、化合物収率 97.3%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

To 0.7 g (2.0 mM) of 2-(p-acetoxyphenyl)-6hexylbenzothiazole, 0.25 g (6.0 mM) of sodium hydroxide and 50 ml of ethanol, followed by stirring for 10 hours at room temperature. After the reaction, the reaction mixture was poured into water, and 2 ml of concentrated hydrochloric was added thereto to precipitate a crystal. The crystal was recovered by filtration and sufficiently washed with water, followed by drying to obtain 0.6 g of 2-(p-hydroxyphenyl)-6-hexylbenzothiazole (Yield: 96.5%).

後処理

  1. customAfter the reaction
  2. additionwas added
  3. customto precipitate a crystal
  4. filtrationThe crystal was recovered by filtration
  5. washsufficiently washed with water
  6. customby drying

出典と根拠

ORDレコード
ord-4c8099d312d04038b724444911b4d3c4
出典データセット
uspto-grants-1994_02
特許番号
US05284599

反応ノート

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