Thionyl Chloride → HCID 53883256、化合物

反応式

[CH3:1][C@@H:2]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3]O.S(Cl)([Cl:14])=O>>[CH3:1][C@@H:2]([CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[CH2:3][Cl:14]

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 11804940(S)-2-methyl-3-phenylpropan-1-ol

生成物 1

HCID 53883256HCID 53883256、化合物

実験手順

In accordance with the general procedure described in Example 8 (a), 22.5 g (0.15 mol) of (S)-2-methyl-3-phenylpropanol are reacted with 20.2 g (0.17 mol) of thionyl chloride, and the crude product is distilled under a high vacuum (18 torr) to give (b) (b.p. 110°-112° C.) as a colourless oil.

後処理

distillationthe crude product is distilled under a high vacuum (18 torr)

出典と根拠

ORDレコード: ord-43d5fd277fdc4062bb243f7770933b6e
出典データセット: uspto-grants-1994_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05288928

反応ノート

読み込み中…

参加物