Tetrahydrofurfuryl alcohol → HCID 21997501、化合物

HRID 1977260ノート

反応式

HRID 1977260 の反応式
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:19]=[CH:18][C:13]([C:14](OC)=[O:15])=[CH:12][CH:11]=1.O1CCCC1CO.O.[NH2:28][NH2:29]>O>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:19]=[CH:18][C:13]([C:14]([NH:28][NH2:29])=[O:15])=[CH:12][CH:11]=1

参加物

5

反応物 3

HCID 7360Tetrahydrofurfuryl alcoholHCID 24654Hydrazine hydrate (1:1)HCID 21997570HCID 21997570、化合物

生成物 1

HCID 21997501HCID 21997501、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of methyl 4-(6-methoxy-n-hexyloxy)benzoate (17.05 g) in 1:1 tetrahydrofuran-methanol (300 ml) was treated with hydrazine monohydrate (66 ml) and refluxed for 15 hours then cooled to room temperature. The reaction mixture was poured into water and the resulting precipitate collected by filtration, washed thoroughly with water then dried under hi-vacuum at 50° C. to give 4-(6-methoxy-n-hexyloxy)benzohydrazide (15.63 g) as a white solid.

後処理

  1. temperaturerefluxed for 15 hours
  2. filtrationthe resulting precipitate collected by filtration
  3. washwashed thoroughly with water
  4. customthen dried under hi-vacuum at 50° C.

出典と根拠

ORDレコード
ord-f1541a554f834b3c85aee3faaf5f3224
出典データセット
uspto-grants-2001_05
特許番号
US06232290B1

反応ノート

読み込み中…