HCID 21993984、化合物 → 5-Thia-1,8b-diazaacenaphthylene-4-carbaldehyde

HRID 1978503ノート

反応式

HRID 1978503 の反応式
[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([CH2:13][OH:14])=[CH:4]2>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([CH:13]=[O:14])=[CH:4]2

参加物

4

反応物 1

HCID 21993984HCID 21993984、化合物

生成物 1

HCID 219941445-Thia-1,8b-diazaacenaphthylene-4-carbaldehyde

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 6212Chloroform溶媒

実験手順

To a solution of 1.073 g (5.253 mM) of 5-thia-1,8b-diazaacenaphthylene-4-methanol in 30 ml of chloroform was added 3 g of activated manganese dioxide (Aldrich) and the mixture was stirred at room temperature for 4 hours. This reaction mixture was filtered and the filter cake was washed with chloroform. The filtrate and washes were pooled and the solvent was distilled off under reduced pressure. The crude 5-thia-1,8b-diazaacenaphthylene-4-carbaldehyde thus obtained was not purified but used as it was in the next reaction.

後処理

  1. filtrationThis reaction mixture was filtered
  2. washthe filter cake was washed with chloroform
  3. distillationthe solvent was distilled off under reduced pressure

出典と根拠

ORDレコード
ord-e8259484c79a4632a98412e63dc8f543
出典データセット
uspto-grants-2001_05
特許番号
US06235731B1

反応ノート

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