Diphosgene → HCID 21201246、化合物
反応式
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[CH:9]1[O:13][CH2:12][CH2:11][O:10]1.Cl[C:15](OC(Cl)(Cl)Cl)=[O:16]>C(OCC)(=O)C.C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([N:6]=[C:15]=[O:16])=[CH:4][C:3]=1[CH:9]1[O:10][CH2:11][CH2:12][O:13]1参加物
5
反応条件
- 温度
- 22.5 °C
実験手順
2.0 g of 4-chloro-3-(1,3-dioxolan-2-yl)-aniline in 25 ml of ethyl acetate were added to a solution of 3.0 g of trichloromethyl chloroformate in 50 ml of toluene at about 20-25° C. This mixture was stirred for 2 hours at 20-25° C. and then for a further 5 hours at the reflux temperature. Thereafter, the reaction mixture was evaporated down and the residue was dried under greatly reduced pressure.
後処理
- waitfor a further 5 hours at the reflux temperature
- customThereafter, the reaction mixture was evaporated down
- customthe residue was dried under greatly reduced pressure
出典と根拠
- ORDレコード
- ord-d214111a7ab24df6b7c784f47ea44d49
- 出典データセット
- uspto-grants-2001_05
- 特許番号
- US06239074B1
反応ノート
読み込み中…