2-Chlorobenzaldehyde → HCID 56616910、化合物

反応式

[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[NH2:10][CH2:11][P:12]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C([O:28]C(C)C)(C)C>C(O)C>[Cl:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[N:10][CH2:11][P:12](=[O:28])([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

参加物

反応条件

温度: 50 °C

実験手順

2.18 g. (0.015 mol) o-chlorobenzaldehyde is added dropwise to a solution of 3.5 g. (0.015 mol) aminomethyldiphenylphosphine in 150 ml. ethanol at ambient temperature. After evaporation of the solvent by heating to 50° C. under a slight vacuum, a clear yellow oil is obtained which is taken up hot in 50 ml. of a mixture of diisopropyl ether and ethanol (25/1 v/v). After cooling to 10° C., filtering and drying at 40° C. in vacuo, there are obtained 4.9 g. of crystals of the desired product; m.p. 89° C.