2,5-Hexanedione → 2,5-Dimethylpyrrolidine-1-propanol
反応式
[CH3:1][C:2](=O)[CH2:3][CH2:4][C:5](=O)[CH3:6].[NH2:9][CH2:10][CH2:11][CH2:12][OH:13]>[Pd].C(O)C>[OH:13][CH2:12][CH2:11][CH2:10][N:9]1[CH:2]([CH3:1])[CH2:3][CH2:4][CH:5]1[CH3:6]参加物
5
実験手順
A total of 3 moles of 2,5-hexanedione, 3 moles of 3-amino-1propanol, 10 g of 10% Pd/C, and 500 ml of ethanol were charged to an autoclave. The reaction mixture was pressured up to 1100 psi of H2 and kept for 3 hours at 100° C. Distillation yielded 170 g of N-(3-hydroxypropyl)-2,5-dimethylpyrrolidine (b.p.=119° C. at 25 mm).
後処理
- distillationDistillation
出典と根拠
- ORDレコード
- ord-9b81856340254beda417e4d710f7b50b
- 出典データセット
- uspto-grants-1984_11
- 特許番号
- US04483833
反応ノート
読み込み中…