Diethyl Ether → 5-Methylcyclodec-5-en-1-one
反応式
[C:1]([CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][C:5]1([CH:11]=[CH2:12])[OH:10])([CH3:3])=[CH2:2].C(OCC)C>O1CCCC1>[CH3:3][C:1]1[CH2:2][CH2:12][CH2:11][C:5](=[O:10])[CH2:6][CH2:7][CH2:8][CH2:9][CH:4]=1参加物
4
実験手順
A mixture of 2-isopropenyl-1-vinylcyclohexan-1-ol (0.166 g; 10-3 mol) and dichloro-bis-(benzonitrile)-palladium(II) (0.038 g; 10-4 mol) in tetrahydrofuran (5 cc) is kept at a temperature of the order of 20° C. under an inert atmosphere. After a reaction time of 24 hours, diethyl ether (75 cc) is added and the mixture is then washed with water (5×15 cc). After drying over magnesium sulphate, filtration and evaporation of the solvent under reduced pressure (20 mm Hg; 2.7 kPa), 5-methylcyclodec-5-en-1-one (0.070 g) is obtained, which has the following characteristics:
後処理
- customis kept at a temperature of the order of 20° C. under an inert atmosphere
- washthe mixture is then washed with water (5×15 cc)
- dry with materialAfter drying over magnesium sulphate, filtration and evaporation of the solvent under reduced pressure (20 mm Hg; 2.7 kPa)
出典と根拠
- ORDレコード
- ord-42877230e9314233880ed25bbc81ecd3
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04510330
反応ノート
読み込み中…