HCID 13424190、化合物 → 7-Amino-2,3-dihydro-1lambda6-benzothiophene-1,1-dione
反応式
[N+:1]([C:4]1[C:9]2[S:10](=[O:14])(=[O:13])[CH:11]=[CH:12][C:8]=2[CH:7]=[CH:6][CH:5]=1)([O-])=O.[H][H]>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[C:9]2[S:10](=[O:14])(=[O:13])[CH2:11][CH2:12][C:8]=2[CH:7]=[CH:6][CH:5]=1参加物
5
実験手順
7-Nitrobenzo[b]thiophene-1,1-dioxide (19 g, Example 17) was hydrogenated in 200 ml of ethyl acetate over 1.0 g of 10% palladium-on-charcoal catalyst at 500 pounds-per-square-inch of pressure and 100° C. until no more hydrogen gas was absorbed. The mixture was filtered through celite, and the filtrate was concentrated in vacuo. The solid residue was recrystallized from 1-chlorobutane to yield 13.2 g of the title compound; m.p. 117°-119° C.
後処理
- customwas absorbed
- filtrationThe mixture was filtered through celite
- concentrationthe filtrate was concentrated in vacuo
- customThe solid residue was recrystallized from 1-chlorobutane
出典と根拠
- ORDレコード
- ord-3b9ea3e7ea74481badbc7fd0f887e05c
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04514211
反応ノート
読み込み中…