Potassium thiocyanate → (2,2-Dichloro-3,3-dimethylcyclopropyl)methyl thiocyanate
反応式
[Cl:1][C:2]1([Cl:9])[C:4]([CH3:6])([CH3:5])[CH:3]1[CH2:7]Cl.[S-:10][C:11]#[N:12].[K+]>C(O)C>[Cl:1][C:2]1([Cl:9])[C:4]([CH3:6])([CH3:5])[CH:3]1[CH2:7][S:10][C:11]#[N:12]参加物
4
実験手順
1.87 g of 2,2-dichloro-3,3-dimethyl-1-chloromethylcyclopropane and 1.0 g of potassium thiocyanate were suspended in 20 ml of ethanol, and the suspension was refluxed for 12 hours. Ethanol was evaporated, and 20 ml of water was added. The mixture was extracted with toluene. The toluene layer was washed with water and dried over sodium sulfate. The toluene was then evaporated under reduced pressure to give 1.80 g of 2,2-dichloro-3,3-dimethylcyclopropylmethyl thiocyanate, the desired compound shown above. The boiling point of the product was 115° C. at 200 mmHg.
後処理
- temperaturethe suspension was refluxed for 12 hours
- customEthanol was evaporated
- addition20 ml of water was added
- extractionThe mixture was extracted with toluene
- washThe toluene layer was washed with water
- dry with materialdried over sodium sulfate
- customThe toluene was then evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-b3a5eab249d44e83841cdbc99e247a0d
- 出典データセット
- uspto-grants-1985_04
- 特許番号
- US04514418
反応ノート
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