Pyrazole → Metazachlor

HRID 1981602

反応式

HRID 1981602 の反応式
[Cl:1][CH2:2][C:3]([N:5]([CH2:14]Cl)[C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])=[O:4].[NH:16]1[CH:20]=[CH:19][CH:18]=[N:17]1>C1(C)C=CC=CC=1>[Cl:1][CH2:2][C:3]([N:5]([CH2:14][N:16]1[CH:20]=[CH:19][CH:18]=[N:17]1)[C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[CH:8][C:7]=1[CH3:13])=[O:4]

参加物

4

反応物 2

HCID 1048PyrazoleHCID 130698822-Chloro-N-(chloromethyl)-N-(2,6-dimethylphenyl)acetamide

生成物 1

HCID 49384Metazachlor

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

43.9 parts by weight of 2-chloro-2',6'-dimethyl-N-chloromethyl acetanilide and 25.8 parts by weight of pyrazole are stirred for 7 hours at 90° C. in 120 parts by volume of toluene. After the mixture has cooled it is filtered, and the filtrate is washed 3 times with water, each time with 50 parts by volume, and dried over sodium sulfate. The solvent is evaporated and the residue pasted with 50 parts by volume of petroleum ether to give 39.1 parts by weight of 2-chloro-2',6'-dimethyl-N-(pyrazol-1-yl-methyl)-acetanilide, m.p.: 81° C.

後処理

  1. temperatureAfter the mixture has cooled it
  2. filtrationis filtered
  3. washthe filtrate is washed 3 times with water
  4. dry with materialeach time with 50 parts by volume, and dried over sodium sulfate
  5. customThe solvent is evaporated

出典と根拠

ORDレコード
ord-8adae3aea54c42aab829a92824e3ab1a
出典データセット
uspto-grants-1986_06
特許番号
US04593104

関連ノート

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