Phenyl 2-(4-nitrophenoxy)benzoate → Phenyl 2-(4-aminophenoxy)benzoate

HRID 1982359ノート

反応式

HRID 1982359 の反応式
[N+:1]([C:4]1[CH:25]=[CH:24][C:7]([O:8][C:9]2[CH:23]=[CH:22][CH:21]=[CH:20][C:10]=2[C:11]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:12])=[CH:6][CH:5]=1)([O-])=O.[H][H]>C(O)C.[Pd]>[NH2:1][C:4]1[CH:25]=[CH:24][C:7]([O:8][C:9]2[CH:23]=[CH:22][CH:21]=[CH:20][C:10]=2[C:11]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:12])=[CH:6][CH:5]=1

参加物

5

反応物 2

HCID 23316310Phenyl 2-(4-nitrophenoxy)benzoateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 23316308Phenyl 2-(4-aminophenoxy)benzoate収率 92%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

9 g of phenyl 2-(4'-nitrophenoxy)benzoate, prepared as described in Example 1, are contacted with hydrogen in 50 cm3 of ethanol, in the presence of 5% palladium (100 mg) on coal. After recrystallization in 100 cm3 of a methanol-water mixture (50--50 by volume), 7.52 g of phenyl 2-(4'-aminophenoxy)benzoate (m.p. 102° C.) are obtained (yield: 92%).

後処理

  1. customAfter recrystallization in 100 cm3 of a methanol-water mixture (50--50 by volume)

出典と根拠

ORDレコード
ord-2b5f8d4c882940be86553507d73954d7
出典データセット
uspto-grants-1986_06
特許番号
US04596680

反応ノート

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