Sodium Iodide → HCID 131712367、化合物

反応式

[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[Cl:12])[NH:5][CH2:6][CH2:7]Cl.[C:13]([NH2:17])([CH3:16])([CH3:15])[CH3:14].[I-].[Na+]>C(OCC)C>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][CH2:6][CH2:7][NH:17][C:13]([CH3:16])([CH3:15])[CH3:14])[CH:9]=[CH:10][C:11]=1[Cl:12]

参加物

実験手順

15.0 g of 2-(3,4-dichloroanilino)ethylchloride, 19.2 g of tert.butylamine and approximately 1 g of sodium iodide were stirred for 26 hours at 90° C. After having been left to stand the weekend over at room temperature, the product was taken up in diethyl ether, washed with successively 2N sodium hydroxide solution and sodium bicarbonate solution and dried. After evaporating the solvent, 15.85 g of product were obtained, which were purified by column chromatography and then converted into the HCl salt with an alcoholic HCl solution. Melting point 206°-207° C.