Thionyl Chloride → 4-bromo-3-i-propyl-1-(chloromethyl)-1H-pyrazole hydrochloride
反応式
[Br:1][C:2]1[C:3]([CH:9]([CH3:11])[CH3:10])=[N:4][N:5]([CH2:7]O)[CH:6]=1.S(Cl)([Cl:14])=O>ClCCl>[ClH:14].[Br:1][C:2]1[C:3]([CH:9]([CH3:11])[CH3:10])=[N:4][N:5]([CH2:7][Cl:14])[CH:6]=1参加物
4
実験手順
1.29 g of 4-bromo-3-i-propyl-1H-pyrazole-1-ylmethanol was dissolved to 20 ml of dichloromethane. 2 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 1.28 g of 4-bromo-3-i-propyl-1-(chloromethyl)-1H-pyrazole hydrochloride.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-9f9cc6fdf1184ec1ac53d8a1a69956e6
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07541374B2
反応ノート
読み込み中…