Ethyl Acrylate → HCID 43365416、化合物
反応式
[CH2:1]([C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[CH:5][CH:4]=1)[CH3:2].[C:10]([O:14][CH2:15][CH3:16])(=[O:13])[CH:11]=[CH2:12]>C(O)(=O)C>[CH2:1]([C:3]1[CH:9]=[CH:8][C:6]([NH:7][CH2:12][CH2:11][C:10]([O:14][CH2:15][CH3:16])=[O:13])=[CH:5][CH:4]=1)[CH3:2]参加物
4
実験手順
To a solution of 4-ethyl aniline (10.00 g) in acetic acid (20 mL) was added ethyl acrylate (8.26). The mixture was heated to 70° for 3.5 hours. The mixture was allowed to cool to room temperature. The mixture was partitioned between dichloromethane and water, and was extracted three times. The combined organics were washed once with brine, dried with sodium sulfate, filtered, and concentrated. The mixture was taken on to the next step. MS (ESI+) for C13H19NO2 m/z 223.1 (M+H)+.
後処理
- temperatureThe mixture was heated to 70° for 3.5 hours
- customThe mixture was partitioned between dichloromethane and water
- extractionwas extracted three times
- washThe combined organics were washed once with brine
- dry with materialdried with sodium sulfate
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-4e517e21fce64bc19a065b5cd4c25bf7
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07544717B2
反応ノート
読み込み中…