Hydrazine hydrate (1:1) → (1SR,8RS)-5-(2,2-Dimethyl-propyl)-6-methyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

反応式

[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[C:3](=O)[C:2]2=O.C(OP([CH:18]([CH3:26])[C:19](=O)[CH2:20][C:21]([CH3:24])([CH3:23])[CH3:22])(=O)OCC)C.O.[NH2:28][NH2:29]>>[CH3:22][C:21]([CH3:24])([CH3:23])[CH2:20][C:19]1[C:18]([CH3:26])=[C:3]2[C:2]([CH:1]3[CH2:7][CH:4]2[CH2:5][CH2:6]3)=[N:29][N:28]=1

参加物

反応物 3

HCID 24654Hydrazine hydrate (1:1)

HCID 138696Bicyclo(2.2.1)heptane-2,3-dione

HCID 86617458(1,4,4-Trimethyl-2-oxo-pentyl)-phosphonic acid diethyl ester

生成物 1

HCID 69059729(1SR,8RS)-5-(2,2-Dimethyl-propyl)-6-methyl-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

実験手順

light-yellow oil. MS (ESI): 297.1 (MH+). Prepared from bicyclo[2.2.1]heptane-2,3-dione, (1,4,4-trimethyl-2-oxo-pentyl)-phosphonic acid diethyl ester, hydrazine monohydrate.

出典と根拠

ORDレコード: ord-176fec6a1ae14e0cb5e5b253028b237f
出典データセット: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07547697B2

反応ノート

読み込み中…