HCID 68844381、化合物 → HCID 68843919、化合物
反応式
[CH3:1][N:2]1[C:9](=[O:10])[CH:8]2[N:11](C(OCC3C=CC=CC=3)=O)[CH:4]([CH2:5][CH2:6][CH2:7]2)[C:3]1=[O:22].[H][H]>C(OCC)(=O)C.[Pd]>[CH3:1][N:2]1[C:9](=[O:10])[CH:8]2[NH:11][CH:4]([CH2:5][CH2:6][CH2:7]2)[C:3]1=[O:22]参加物
5
実験手順
A stirred suspension of benzyl 3-methyl-2,4-dioxo-3,9-diazabicyclo[3.3.1]nonane-9-carboxylate (742 mg, 2.454 mmol) and 10% Pd—C (100 mg) in ethyl acetate (40 ml) was hydrogenated under balloon pressure of hydrogen overnight. The suspension was filtered to remove the catalyst and the filtrate was evaporated to dryness to afford 3-methyl-3,9-diazabicyclo[3.3.1]nonane-2,4-dione as a white solid (377 mg). MS: m/e 169 (MH+).
後処理
- filtrationThe suspension was filtered
- customto remove the catalyst
- customthe filtrate was evaporated to dryness
出典と根拠
- ORDレコード
- ord-7e218f028c4e482cb111dd6c3561efd7
- 出典データセット
- uspto-grants-2009_06
- 特許番号
- US07547690B2
反応ノート
読み込み中…