HCID 68871818、化合物 → HCID 86623345、化合物
反応式
[CH2:1]([NH:3][C:4]1[C:9]([N+:10]([O-])=O)=[CH:8][N:7]=[C:6]([O:13][C:14]2[CH:15]=[C:16]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:26])([CH3:25])[CH3:24])[CH:17]=[CH:18][CH:19]=2)[CH:5]=1)[CH3:2]>C(O)C.[Pd]>[NH2:10][C:9]1[C:4]([NH:3][CH2:1][CH3:2])=[CH:5][C:6]([O:13][C:14]2[CH:15]=[C:16]([NH:20][C:21](=[O:27])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH:17]=[CH:18][CH:19]=2)=[N:7][CH:8]=1参加物
4
実験手順
The product from Step 2 (1.26 g, 3.3 mmol) in ethanol (20 mL) was hydrogenated for 3 hours in the presence of 10% palladium on carbon under H2 (50 psi). After filtration of the catalyst through Kieselguhr, the filtrate was concentrated in vacuo to afford the title compound (0.81 g, 70%). MS (ES+) m/e 345 [M+H]+.
後処理
- filtrationAfter filtration of the catalyst through Kieselguhr