Water → HCID 68875466、化合物
反応式
[O:1]=[C:2]1[NH:7][CH:6]=[C:5]([C:8](Cl)=[O:9])[CH:4]=[CH:3]1.[NH2:11][C:12]1[CH:13]=[C:14]([O:18][C:19]2[N:24]=[CH:23][C:22]3[N:25]=[C:26]([C:30]4[C:31]([NH2:35])=[N:32][O:33][N:34]=4)[N:27]([CH2:28][CH3:29])[C:21]=3[CH:20]=2)[CH:15]=[CH:16][CH:17]=1.O>N1C=CC=CC=1>[NH2:35][C:31]1[C:30]([C:26]2[N:27]([CH2:28][CH3:29])[C:21]3[CH:20]=[C:19]([O:18][C:14]4[CH:13]=[C:12]([NH:11][C:8]([C:5]5[CH:4]=[CH:3][C:2](=[O:1])[NH:7][CH:6]=5)=[O:9])[CH:17]=[CH:16][CH:15]=4)[N:24]=[CH:23][C:22]=3[N:25]=2)=[N:34][O:33][N:32]=1参加物
5
実験手順
The product of Step 1 (93 mg, 0.6 mmol) was added to a solution of the product of Example 3 (200 mg, 0.6 mmol) in pyridine (1 mL) and the resulting mixture was allowed to stir at rt for 30 min. The solution was poured into H2O and the precipitate which formed as filtered, washed with H2O and Et2O and dried to give the title compound as a tan solid (150 mg, 55%). MS (ES+) m/e 459 [M+H]+.