反応式
ClS(C1C=C(C=CC=1F)C(O)=O)(=O)=O.[CH:15]([NH2:18])([CH3:17])[CH3:16].[Cl:19][C:20]1[CH:28]=[C:27]([F:29])[C:26]([S:30](NCC)(=[O:32])=[O:31])=[CH:25][C:21]=1[C:22]([OH:24])=[O:23]>>[Cl:19][C:20]1[CH:28]=[C:27]([F:29])[C:26]([S:30]([NH:18][CH:15]([CH3:17])[CH3:16])(=[O:32])=[O:31])=[CH:25][C:21]=1[C:22]([OH:24])=[O:23]参加物
4
実験手順
1.002 g (3.6 mmol) 3-chlorosulfonyl-4-fluorobenzoic acid was added to 0.94 mL (10.9 mmol) isopropylamine following the general procedure in for 2-chloro-5-[(ethylamino)sulfonyl]-4-fluorobenzoic acid. Crude product was used in subsequent step without further purification
後処理
- customCrude product was used in subsequent step without further purification
出典と根拠
- ORDレコード
- ord-7c6c22f29f2f4b848cc36ba4e4c756c9
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07645771B2
関連ノート
読み込み中…