反応式
ClS(C1C=C(C=CC=1F)C(O)=O)(=O)=O.[CH:15]1([NH2:18])[CH2:17][CH2:16]1.[Cl:19][C:20]1[CH:28]=[C:27]([F:29])[C:26]([S:30](NCC)(=[O:32])=[O:31])=[CH:25][C:21]=1[C:22]([OH:24])=[O:23]>>[Cl:19][C:20]1[CH:28]=[C:27]([F:29])[C:26]([S:30]([NH:18][CH:15]2[CH2:17][CH2:16]2)(=[O:32])=[O:31])=[CH:25][C:21]=1[C:22]([OH:24])=[O:23]参加物
4
実験手順
1.005 g (3.6 mmol) 3-chlorosulfonyl-4-fluorobenzoic acid was added to 0.76 mL (10.9 mmol) cyclopropylamine following the general procedure in for 2-chloro-5-[(ethylamino)sulfonyl]-4-fluorobenzoic acid. Crude product was used in subsequent step without further purification
後処理
- customCrude product was used in subsequent step without further purification
出典と根拠
- ORDレコード
- ord-a951a2a29afa4151a97c8004fedd0b81
- 出典データセット
- uspto-grants-2010_01
- 特許番号
- US07645771B2
関連ノート
読み込み中…