Quinolinic Acid → 4,6-Diamino-1,3-benzenediol pyridinedicarboxylate

HRID 1994174

反応式

HRID 1994174 の反応式
Cl.Cl.[NH2:3][C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([OH:11])=[CH:6][C:5]=1[OH:12].[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([OH:21])=[O:20])[C:14]=1[C:22]([OH:24])=[O:23].N1C=CC=C(C([O-])=O)C=1C([O-])=O.[Na+].[Na+]>O.[OH-].[Na+]>[NH2:3][C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([OH:11])=[CH:6][C:5]=1[OH:12].[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([O-:21])=[O:20])[C:14]=1[C:22]([O-:24])=[O:23]

参加物

6

反応物 3

HCID 1066Quinolinic AcidHCID 27336484,6-Diaminoresorcinol Dihydrochloride2 回HCID 13430307Disodium pyridinedicarboxylate

生成物 1

HCID 866229924,6-Diamino-1,3-benzenediol pyridinedicarboxylate

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 14798Sodium Hydroxide溶媒

実験手順

7 parts by weight of 4,6-diamino-1,3-benzenediol dihydrochloride was dissolved in 33 parts by weight of water deaerated with nitrogen. 5.347 parts by weight of pyridinedicarboxylic acid was dissolved in 64 parts by weight of 1M sodium hydroxide solution and deaerated with nitrogen. The 4,6-diamino-1,3-benzenediol dihydrochloride solution was added dropwise to the disodium pyridinedicarboxylate solution over 10 minutes to form a white precipitate of 4,6-diamino-1,3-benzenediol/pyridinedicarboxylate. In this case, the reaction temperature was kept at 90° C. The obtained salt was filtered, dispersed and mixed into 3,000 parts by weight of water deaerated with nitrogen, and then filtered again. This dispersion, mixing and filtration operation was repeated three times.

出典と根拠

ORDレコード
ord-1310b28b3fb84d7aac74fa2ad2af9861
出典データセット
uspto-grants-2010_01
特許番号
US07652124B2

関連ノート

読み込み中…