反応式
[N+:1]([C:4]1[CH:15]=[CH:14][C:13]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][C:18]=2[Cl:27])=[CH:12][C:5]=1[O:6][CH:7]([CH3:11])[C:8](O)=[O:9])([O-:3])=[O:2].S(Cl)([Cl:30])=O>C1(C)C=CC=CC=1>[N+:1]([C:4]1[CH:15]=[CH:14][C:13]([O:16][C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][C:18]=2[Cl:27])=[CH:12][C:5]=1[O:6][CH:7]([CH3:11])[C:8]([Cl:30])=[O:9])([O-:3])=[O:2]参加物
4
反応条件
- 温度
- 67 °C
実験手順
2-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxy]propionic acid (100 grams) and toluene (40 ml) were charged into a glass reaction vessel equipped with a magnetic stirrer. The mixture was heated on a steam bath until a solution was obtained. The solution was allowed to cool and thionyl chloride (100 ml) was added dropwise with stirring. After the addition was completed, the mixture was warmed to 67° C. with continued stirring for a period of about 21/2 hours. After this time the mixture was stripped of solvent in a rotary evaporator under reduced pressure leaving as the residue 105 grams of the desired product, 2-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxy]propionyl chloride as a burgundy colored viscous oil.
後処理
- customequipped with a magnetic stirrer
- temperatureThe mixture was heated on a steam bath until a solution
- customwas obtained
- temperatureto cool
- additionAfter the addition
- stirringwith continued stirring for a period of about 21/2 hours
- customAfter this time the mixture was stripped of solvent in a rotary evaporator under reduced pressure
出典と根拠
- ORDレコード
- ord-f6e812eecfe14b80af0abbeb1904c913
- 出典データセット
- uspto-grants-1983_09
- 特許番号
- US04402729
関連ノート
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