化工社化工社 化学情報印刷レポート · 研究参考用
Triethyl orthoacetate → 3-Methyl-6-phenyl[1,2,4]triazolo[4,3-a]pyrazine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethyl orthoacetate | HCID 66221 | — |
| 反応物 | 2-Hydrazinyl-5-phenylpyrazine | HCID 13199867 | — |
| 生成物 | 3-Methyl-6-phenyl[1,2,4]triazolo[4,3-a]pyrazine | HCID 13199874 | — |
反応手順
A solution of 0.5 g. (0.0027 mole) of 2-hydrazino-5-phenylpyrazine in 5.0 ml. of triethyl orthoacetate is heated under reflux for 5 hours. The crystalline product precipitates from the hot reaction solution, and at the end of the heating period the mixture is cooled and the product is collected. Recrystallization from ethanol gives 0.36 g. of the product of the example, m.p. 192°-195° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04402958 |
| 出典データセット | uspto-grants-1983_09 |
| ORD ID | ord-d0914a405b454da587388b08131ff14a |
| 出典メモ | uspto-grants-1983_09 |