Sodium Hydroxide → 2-Hydroxy-6-nitroquinoline-3-carboxylic acid
反応式
[N+:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[C:8]([C:15]([O:17]CC)=[O:16])=[CH:7]2)([O-:3])=[O:2].[OH-].[Na+]>Cl>[N+:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[C:8]([C:15]([OH:17])=[O:16])=[CH:7]2)([O-:3])=[O:2]参加物
4
実験手順
A mixture of 9.7 g (37 mmol) of the above ester and 200 ml of 1 N sodium hydroxide is heated on the steam bath for 11/4 hours. The resulting suspension is poured over ice and acidified with 250 ml of 1 N hydrochloric acid. The solid is collected by filtration and washed with water and ethanol to give 8.15 g of the title acid, mp>310° C.
後処理
- temperatureis heated on the steam bath for 11/4 hours
- additionThe resulting suspension is poured over ice
- filtrationThe solid is collected by filtration
- washwashed with water and ethanol
出典と根拠
- ORDレコード
- ord-95f565320e094a9fa727265b2fd66d75
- 出典データセット
- uspto-grants-1983_09
- 特許番号
- US04404201
反応ノート
読み込み中…